In June 1791, Louis XVI and his immediate family made a dash for the nearest friendly border, that of the Austrian Netherlands in modern Belgium (Queen Marie Antoinette being a sister to Leopold II, Archduke of Austria and Holy Roman Emperor).

In Varennes, Louis and his family were arrested by Jean-Baptiste Drouet, the local postmaster, who had been alerted by a message received from nearby Sainte-Menehould.

It is said that at Sainte-Menehould, where the escaping party had spent the previous night, a merchant alerted the town authorities of their presence after recognizing the King's face on an Assignat as Louis tried to buy something from a shop.

The royal family was returned to the Tuileries in humiliating captivity, and Louis and Marie-Antoinette were subsequently guillotined in 1793.

Located in the Zone rouge, Varennes was completely destroyed during the First World War but was reconstructed afterwards.