A manga adaptation by Eiji Kaneda ran from 2012 to 2014, and a second one, illustrated by Anjue Hino, began serialization in 2016.

The story follows two men, Hiraga Josef Kō and Roberto Nicholas, who work for the mysterious organization The Seat of the Saints (聖徒の座, Seito no Za), an element of the Vatican dedicated to investigating alleged miracles; during their work, they usually find themselves involved in mysterious murder cases, which they often end up investigating.

Eventually they cross paths with Galdoune, an ancient organization that secretly aims to control the Vatican and since the Middle Ages is involved in obscure alchemic and scientific experiments in search of a way to reach immortality.

A manga adaptation by Eiji Kaneda launched in Kadokawa's Comic Kai magazine on January 24, 2012.

Joseph tells Lauren the story of a man he met, who The series has sold over 950,000 copies in Japan.