Vaux-Marquenneville (French pronunciation: [vo maʁkɛnvil]; Picard: Veux-Martchéneville) is a commune in the Somme department in Hauts-de-France in northern France.

The name Vaux derives from "vale" or "valley" and Marquenneville comes from the domain of someone called Marca.

In 1943 work began to build a V1 missile launch ramp at "Le Mont" in Marquenneville.

A German army deserter hid in a hangar under a pile of wheat and after fruitless search by the Wehrmacht, the soldier, with the help of the French Resistance escaped from France to Spain and return to his own home.

Vaux-Marquenneville received the Croix de Guerre with Bronze Star from the Secretary of State for War who said: "This courageous village, badly damaged during the Second World War, was delivered by faith and hard work".