[1] The burial mounds located to the south and north of Velykomykhailivka testify to the settlement of this area during the Bronze Age.

In 1776, the governor of Azov, Vasily Chertkov [ru], replaced them with the state military settlement of Mykhailivka.

[1] In 1913, Velykomykhailivka had 1059 households, 5 schools, a medical and veterinary hospital, a post office, a brick and tile factory, three steam mills, two steam oil mills, a warehouse for agricultural implements and a telephone exchange.

After the establishment of the Ukrainian Soviet Socialist Republic, Velykomykhailivka was blacklisted by the Bolsheviks.

[2] During World War II, Velykomykhailivka was liberated by units of 1164th and 1168th rifle regiments.