The man-made Venetian Islands and non-bridge portions of the causeway were created by materials which came from the dredging of the bay.

The Venetian Causeway follows the original route of the Collins Bridge, a wooden 2.5 mi (4 km) long structure built in 1913 by John S. Collins and Carl G. Fisher which opened up the barrier island for unprecedented growth and development.

At the Downtown/Western Beginning of the causeway travelers are greeted by two columns vertically saying "VENETIAN WAY" along with a sign indicating that there is a weight limit .

At the South Beach/Eastern Terminus, drivers must choose whether to go north onto Dade Boulevard or eastbound onto 17th Street to Ocean Drive, Collins Ave/A1A, Lincoln Road, City Hall, The Convention Center, Jackie Gleason Theater and the beach .

[7] In 2023 Miami-Dade County initiated a plan to replace the 11 original bridges along the causeway with higher structures.