Ventura Boulevard is one of the primary east–west thoroughfares in the San Fernando Valley region of the City of Los Angeles, California.

Ventura Boulevard follows an ancient pre-Columbian trading trail that served the Tataviam and Tongva village of Siutcanga, which is at least 4,000 years old.

[2] This 5-acre (2 hm²) park now includes the original nine-room De La Osa Adobe (built in 1849) and a reservoir shaped like a Spanish guitar that collects the springwater.

Also in 1922, around the area of Canoga Avenue south of Ventura Boulevard, Victor Girard purchased 2,886 acres (12 km²) of land and planted over 120,000 pepper, sycamore, and eucalyptus trees, later resulting in the appropriately named Woodland Hills.

[citation needed] In 2015 the Studio City section of Ventura Boulevard, along with Lankershim Boulevard, was the site of CicLAvia, an event sponsored by the Los Angeles County Metropolitan Transportation Authority in which major roads are temporarily closed to motorized vehicle traffic and used for recreational human-powered transport.

In the Seinfeld episode "The Trip, Part 2", Jerry and George were said to be calling from a pay phone on Ventura Boulevard.

In the Treehouse of Horror VI episode of The Simpsons, Ventura Boulevard features as the location of the show's first ever live-action scene.

Tired men in dusty coupés and sedans winced and tightened their grip on the wheel and ploughed on north and west towards home and dinner...I drove past the gaudy neon’s and the false fronts behind them, the sleazy hamburger joints that look like palaces under the colors, the circular drive-ins as gay as circuses with chipper hard-eye car-hops...Behind Encino an occasional light winked...from the homes of screen stars.