His seventh bout came on September 16, 2017, on the undercard of Canelo Álvarez vs. Gennady Golovkin I against Cesar Valenzuela, which he won by second-round technical knockout.

[7] Ortiz, who now had an unblemished record of 13-0, defeated Antonio Orozco by sixth-round technical knockout to win the vacant WBA Gold welterweight title on August 10, 2019, at The Theatre at Grand Prairie, Texas.

[9] Ortiz was originally scheduled to face Samuel Vargas on March 28, 2020, at The Forum, Inglewood, California on the undercard of Canelo Álvarez vs. Billy Joe Saunders.

[12] Ortiz returned to the ring on March 20, 2021, beating Maurice Hooker with another seventh-round technical knockout in Fort Worth, Texas to win the vacant WBO International welterweight title.

[19] Ortiz Jr was scheduled to face Tim Tszyu on August 3, 2024 at BMO Stadium in Los Angeles.

[21] Tszyu required more time to heal from the injury sustained in his previous bout against Sebastian Fundora in March.