Vesperae solennes de Dominica, K. 321, is a sacred choral composition, written by Wolfgang Amadeus Mozart in 1779.

It is scored for SATB choir and soloists, violin I and II, 2 trumpets, 3 trombones colla parte, 2 timpani, and basso continuo (bassoon and organ).

[1] In 1780, Mozart composed another setting of Solemn Vespers, the Vesperae solennes de confessore, which shares many musical similarities with this work.

A setting of the Minor Doxology (Gloria Patri) concludes all movements, each recapitulating the opening theme.

The first three psalms are scored in a vigorous, exuberant manner, contrasting with the strict counterpoint of the a cappella Laudate pueri.