The vice president of the Dominican Republic (Spanish: Vicepresidente de la República Dominicana) is the second-highest political position in the Dominican Republic.

Yet, during that time there were acting vice presidents; this was under the rule of Pedro Santana.

After the inception of the Dominican Republic, the country was run by a Central Governing Junta led by Pedro Santana.

The Constitution of the Dominican Republic has been amended many times, and in some instances the office of the vice president had been eliminated to later be recreated.

Also during the 31 year dictatorship of Rafael Trujillo, the office of the vice president was eliminated or vacated on several occasions.