In 1997, Lopez was wrongfully[5] convicted for honest services mail fraud and sentenced to 27 months in federal prison.

[6][7][8] Lopez’s experience led to a lifetime of activism in criminal justice reform, assisting others who have faced wrongful convictions and working for better public policy.

She has worked on programs to assist inmates in reentering society and managing the negative stigmatism often associated with a criminal conviction, whether warranted or falsely accused.

Lopez introduced and passed HB 1029, the My Safe Florida Condominium Pilot Program, which went into law on July 1, 2024.

Lopez's son, Donald Wolfe III, was the Chief of Staff for Miami City Mayor Francis Suarez.