During her tenure, she was instrumental in the construction of a new governor's residence building, turning the old Washington Place into a museum.

After the family moved to San Francisco, Vicky and a group of her friends started a travel agency when she was a teenager.

In 1988, she helped to start United Laundry Company to service hotels and hospitals, eventually becoming president and CEO.

[4] She was named 1999 Woman of Distinction by Hawaii's Girl Scouts for her work in motivating young women.

[6] Toward that end, she created the Washington Place Foundation to raise funds to build a new residence for the state's governor.

[10] The following year, the University of Hawaii's School of Travel Industry Management presented Cayetano with the 2019 Legacy in Tourism Award.

[11] On August 30, 2021, Cayetano announced her candidacy for the 2022 Hawaii gubernatorial election to succeed term-limited governor David Ige.