Following the death of their son, Luis Pesoa de Figueroa, in 1725, his widow divided the estate into four equal parcels.

Juan Estanislao Zamudio purchased three of the lots, and the fourth was donated by the widow to the Roman Catholic Dominican Order, who established the Convent of Santo Domingo.

Andrés Pazos bought much of the land in 1820, and his rural home was counted in the 1838 census of Buenos Aires Province commissioned by Governor Juan Manuel de Rosas.

A neighboring landowner, Federico Gattemeyer, did likewise in 1908, and the Port Railway opened a station in Villa Domínico in 1909.

The Villa Domínico Community Development and Mutual Aid Society was established on August 28, 1910, and by their initiative, the first fire house was opened in 1912.