The villa was likely originally a rural castle-like structure, which during the centuries of fighting by condottieri of the nearby comunes, became less defensible.
A new villa, tall and imposing, was erected in the late 15th and early 16th century by Pandolfo Petrucci.
The design has been attributed to Baldassarre Peruzzi, perhaps on a similarity of the elevated base to Villa Farnese in Caprarola.
In the 1550s, during the war with the army of the Spanish Empire, the troops of the Marchese di Marignano besieged and took the villa, killing most of those taking refuge within its walls.
[2] The Romanesque-style stone church of Santa Colomba has a cycle of frescoes dating from the 13th to 14th centuries.