Sir Vincent Brian Wigglesworth CBE FRS[1] (17 April 1899 – 11 February 1994) was a British entomologist who made significant contributions to the field of insect physiology.

His most significant contribution was the discovery that neurosecretory cells in the brain of the South American kissing bug, Rhodnius prolixus, secrete a crucial hormone that triggers the prothoracic gland to release prothoracicotropic hormone (PTTH), which regulates the process of metamorphosis.

[6] Wigglesworth was able to distort the developmental phases of the insect by controlling levels of this hormone.

Wigglesworth served in the Royal Field Artillery in France in World War I.

He was named Quick Professor of Biology at the University of Cambridge in 1952, appointed CBE in 1951,[7] and knighted in 1964.