[2]His interest was aroused by lectures of Carl Shipp Marvel[2] and Howard B. Lewis, whom he remembered as being 'extremely enthusiastic about sulfur.

During the fall of 1924, Marvel found him a job as an assistant biochemist at the Philadelphia General Hospital that helped him to teach clinical chemistry at the Graduate School of Medicine, University of Pennsylvania.

[3] Resuming his academic career in 1925, du Vigneaud joined the group of John R. Murlin at the University of Rochester for his PhD thesis.

[2] After a post-doctoral position with John Jacob Abel at Johns Hopkins University Medical School (1927–1928), he traveled to Europe as National Research Council Fellow in 1928–1929, where he worked with Max Bergmann and Leonidas Zervas at the Kaiser Wilhelm Institute for Leather Research in Dresden, and with George Barger at the University of Edinburgh Medical School.

Even before his Nobel-Prize-winning work[1] on elucidating and synthesizing oxytocin[5] and vasopressin via manipulating the AVP gene, he had established a reputation from his research on insulin, biotin, transmethylation, and penicillin.

That work culminated in the publication of a book entitled A Trail of Research in Sulphur Chemistry and Metabolism and Related Fields.