[1] The name Vindobona is now used for Railjet trains between Prague and Graz via Vienna operated by České dráhy and Austrian Federal Railways (ÖBB).

The participating companies Deutsche Reichsbahn (DR), Československé státní dráhy (ČSD) and Österreichische Bundesbahnen (ÖBB) operated one train pair daily, meeting in Czechoslovakia.

In Czechoslovakia trains originally ran on the historic Franz-Josefs-Bahn via Tábor to the border with Austria at České Velenice, later rerouted via the first Czech railway corridor to Brno and Břeclav.

In the period of "Normalization" from 1969 onwards, domestic travel within Czechoslovakia was for some years completely forbidden, occasionally restricted to journeys between Děčín and Tábor.

Later, the mainline via Brno became faster, and the train was rerouted, initially via Havlíčkův Brod and later via Pardubice and Česká Třebová along the Czech international corridor, shortening the journey to 9 hours.

Rolling stock was alternately supplied by the railway companies for a period of two years: The DR used a refurbished pre-war DRG Class SVT 137 unit until 1960, succeeded by MÁVAG 495.0 and 498.0 railcars operated by ČSD, and ÖBB 5145 ("Blue Lightning") DMUs from 1962 to 1964.

As of 2010, trains ran 1,469 kilometres (913 mi) from Villach Hauptbahnhof to Hamburg-Altona via Klagenfurt, Vienna, Brno, Prague, Dresden and Berlin in about 16 hours.