It covers 54 municipalities and is divided into the three sub-zones (Arganda, Navalcarnero, and San Martín), each of which produce different types of wine.

Legal documents indicate a dispute between some monks and a local feudal lord over the ownership of a vineyard.

To the southwest, close to the Sierra de Gredos range, is the San Martín sub-zone, which contains 35% of the DOP's vines.

The four sub-zones of Vinos de Madrid DOP all have long, hot summers and cold winters, typical of a continental climate.

Rainfall varies depending on the sub-zone, but in general it is sparse and falls mainly in spring and autumn.