There is no access to northbound SR 293 from southbound US 29 Business, which is named Memorial Drive north of the intersection, and is a continuation of West Main Street south toward US 29 and Greensboro.

SR 293 heads east as West Main Street, a two-lane undivided road that parallels Norfolk Southern Railway's Danville District.

The state highway veers northeast away from the railroad and passes Averett University prior to its partial cloverleaf interchange with SR 86 (Central Boulevard) adjacent to Danville Regional Medical Center.

The intersection also serves as the western terminus of both US 360 and SR 360; the U.S. Highway heads east concurrent with US 58 Business toward US 58 and South Boston and the state-numbered highway runs concurrently with SR 293 on North Main Street.

The two state highways diverge at a Y intersection, with SR 360 heading east toward Halifax as Richmond Boulevard.