On their 2015 album Symptomatic, Virus Syndicate branched out in Horrorcore and Political hip hop, with songs such a "Watch Your Back" and "Psychopath" having a theme centred on insanity and "Watch Your Back" contains graphic murder descriptions and the song "Do Suttin'" contained political lyrics rapped by Goldfinger denouncing police brutality ("Police are on the loose, they're murderin' civilians"), government corruption, and religion ("The real villains are police, religion, and the crooked politicians").
[2] The song also encourages action in the lyrics in the chorus also rapped by Goldfinger "Do somethin', don't just sit back".
The LP cover featured cartoon artwork and a comic strip about the everyday life of the members of group.
In 2016, their collaboration with Buku, a track called "Worker Bees" was featured on Ubisoft Annecy's extreme snow-sport game "STEEP".
Since their 2017 EP "The Mancunian Way" on Disciple Records, the group have released multiple projects on the label together with big names in the bass music world such as Virtual Riot, Dodge & Fuski, Barely Alive, Infekt and more.