[1] In 1984, he was appointed platoon commander of the separate patrol battalion of the Gagarinskiy district executive committee in Moscow.

He entered the Higher Political College of the Ministry of the Interior of the USSR studying jurisprudence and graduated in 1989.

Two years later he was appointed to the position of the chief of criminal investigation division in Central District Police Department of Moscow.

[1] In 1997, he started to work in the Ministry of Interior of the Russian Federation and on the position of the chief of regional unit no.

[3] On 15 January 2020, he resigned as part of the cabinet, after President Vladimir Putin delivered the Presidential Address to the Federal Assembly, in which he proposed several amendments to the constitution.

On 28 June 2021, the independent Russian media outlet Proekt announced that it would publish an investigation into the property of the relatives of Vladimir Kolokoltsev.

[13][14] In response to the 2022 Russian invasion of Ukraine, on 6 April 2022 the Office of Foreign Assets Control of the United States Department of the Treasury added him to its list of persons sanctioned pursuant to Executive Order 14024.

He has a Doktor Nauk (Doctor of Sciences) of Law, and has the rank of "Honoured Officer of Internal Affairs Authorities".