Member schools were in the National Association of Intercollegiate Athletics (NAIA).
Those in the western part of the state formed in turn the Tennessee Collegiate Athletic Conference (TCAC).
The Appalachian Athletic Conference is the direct successor of the TVAC, and was known as such until the mid-1990s when the addition of schools in Virginia, Kentucky, and North Carolina necessitated the name change.
The TranSouth Athletic Conference, which operated from 1996 to 2013, is sometimes regarded as something of a successor to the TCAC.
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