It was created on 12 February 1645 for Richard Vyvyan, a member of Parliament for Penrhyn, Tregony and St Mawes and Master of the Mint.
His eldest son, the second Baronet, represented St Mawes and Helston in the House of Commons.
The eighth Baronet sat as Conservative Member of Parliament for Cornwall, Okehampton, Bristol and Helston.
The London Gazette no 58640 Friday14 March 2008: Duchy of Cornwall "The Prince of Wales has been pleased to direct Letters Patent to be passed under the Privy Seal of His Royal Highness appointing Sir Ralph Ferrers Alexander Vyvyan Bt of Trelowarren, Helston in the County of Cornwall, High Sheriff of Corwall."
Clara Coltman Rogers Vyvyan, the wife of the 10th Baronet, wrote a number of books using the name C. C. Vyvyan; these include Our Cornwall; Amateur Gardening for Pleasure and Profit; Cornish Silhouettes; Echoes in Cornwall; Gwendra Cove; and Bird Symphony (an anthology).