WESC-FM signed on the air in March 1948 as the FM sister station to WESC 660, simulcasting its country music format.

WESC is the area's network affiliate for Clemson Tigers athletics as well as NASCAR, often calling itself "Your Racin' Station".

WESC-FM was the home station for the syndicated radio show "Country Heartlines", hosted by John Crenshaw.

A nationalized version of Crenshaw’s Cryin’ Lovin’ Laugin’ or Leavin’ show, the program was popular in the 1990s and at one time was carried on over 80 FM stations across the country.

The show consisted of a format of country songs played in between callers calling in with a mix of relationship and love related problems, of which Crenshaw and other listeners would give advice and a lending ear.

The signal comes close to other nearby radio markets, including Charlotte, Atlanta, Columbia, Knoxville and the Tri-Cities.