2DAQ, 4GND, 4GNE, 4GNF, 4GNG, 4RXJ, 4YZ8, 2ND1, 2NCZ54904234135ENSG00000147548ENSMUSG00000054823Q9BZ95Q6P2L6NM_017778NM_023034NM_001001735NM_001081269NM_001308481NM_001308482NP_060248NP_075447NP_001001735NP_001074738NP_001295410NP_001295411Histone-lysine N-methyltransferase NSD3 is an enzyme that in humans is encoded by the WHSC1L1 gene.

[5][6] This gene is related to the Wolf–Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains.

Two alternatively spliced variants have been described.

[6] The WHSC1L1 gene is amplified in several cancers, including lung cancer and head and neck cancer, and may play a role in carcinogenesis.

This article on a gene on human chromosome 8 is a stub.