Owned and operated by the Ion Media subsidiary of the E. W. Scripps Company, the station maintains a transmitter northwest of New Bern, North Carolina.
WPXU-TV (channel 35) in Jacksonville, North Carolina, operates as a full-time satellite of WEPX-TV.
WPXU covers areas of southeastern North Carolina that receive a marginal to non-existent over-the-air signal from WEPX, although there is significant overlap between the two stations' contours otherwise, including in Jacksonville proper.
This was part of a larger move for the FCC to get TV stations off channel 51 to prevent interference with cell phone devices.
[citation needed] In recent years, WPXU has been carried on cable in Carolina Beach, which is within the Wilmington media market.