It was built on land from the Waddesdon Manor estate, which was donated by Dorothy de Rothschild.

Since September 2006, Waddesdon has been part of the Buckingham School Sports Partnership.

Waddesdon School also has Sportsmark status from Sport England, recognising its PE and games provision.

The Dorothy de Rothschild building, which was opened by Lord and Lady Rothschild in 1999, housed the school's Maths and Information and Communication Technology (ICT) departments, and is now the home of the Languages & Computing specialism.

It includes a teaching block that houses the Maths department, a suite of art studios and a sports hall.

The following facilities are available for students at Waddesdon Church of England School: In 1963, shortly after its opening, the school introduced a house system, with four houses competing against each other in sports and academic endeavours.

This new arrangement still retains the previous competitions, but they are now solely between the forms within each year group.

The school promotes a learning culture based on year groups.

In 2023, one of the six Deputy Head Students created an additional motto for the school which reflected the ethos.

The school was adjudged to be "outstanding" in three successive Ofsted reports, and repeatedly improved its exam results.