The new management could not see a future for the line as a financially viable passenger route, and Waddesdon Road, along with the rest of the former Brill Tramway, was closed in late 1935.

The station was heavily used for the transport of construction materials during the building of Baron Ferdinand de Rothschild's estate at Waddesdon Manor in the 1870s and 1880s, but aside from that it saw little use.

In the early 1870s he decided to build a light railway to carry goods between his estates in Buckinghamshire and the A&BR's line at Quainton Road.

[13] The station was initially built with a single low wooden platform, primarily intended for loading and unloading freight.

[12] The station was heavily used during the construction of Baron Ferdinand de Rothschild's estate at Waddesdon Manor in the 1870s and 1880s.

[15] Aside from goods traffic associated with the building of Waddesdon Manor, the station was little used other than for shipping milk from nearby farms to Aylesbury and London.

Goods traffic had dwindled, and unlike other areas served by the former Metropolitan Railway there had not been a growth in population and thus passenger numbers remained low.

[10][25] Upon the withdrawal of London Transport services the railway and stations reverted to the control of the by now almost dormant Oxford & Aylesbury Tramroad Company.

[1] London and North Eastern Railway services (British Rail from 1948) continued to run from London's Marylebone station over the line to Verney Junction via Quainton Road until March 1963,[1] and the LPTB continued to maintain and to operate freight services over the Verney Junction line until 6 September 1947.

[27] After the withdrawal of services from London, Verney Junction station remained open to serve trains on the Oxford–Bletchley line.