Wakefield is an unincorporated community and census-designated place (CDP) within Fulton Township, Lancaster County, Pennsylvania, United States.

[2] It is the largest community within the "Peach Bottom" ZIP code, with the area post office on Pennsylvania Route 272, just north of town.

Wakefield is in southern Lancaster County, in the north-central part of Fulton Township.

PA 272's route is more direct, leading north-northwest through Buck 20 miles (32 km) to Lancaster, while US 222 curves north-northeast through Quarryville and rejoins PA 272 at Willow Street for a 24-mile (39 km) route to the city.

To the south from Wakefield, US 222 leads 7.5 miles (12.1 km) to U.S. Route 1 in Maryland, just north of Conowingo Dam on the Susquehanna River, while PA 272 leads east from Wakefield 9 miles (14 km) to US 1 in Nottingham.