It was founded in Cannstatt, a suburb of Stuttgart in 1780 by Johann Eberhard Walcker [de].

Other important commissions followed rapidly, and Walcker became a pioneer of the "symphonic organ" style in Germany.

Known for distinguished installations and low output, the company built the organ in the Boston Music Hall in Boston, Massachusetts, Zagreb Cathedral in Zagreb, Croatia, University of Latvia,[2] Riga Cathedral and Church of Luther in Riga, Latvia.

The largest Walcker organ in the world had 220 stops and over sixteen thousand pipes.

It was built in 1930s for a state congress hall in Nuremberg and was destroyed by aerial bombings during World War II.