Other guests have included DJ Logic, Big Gigantic, Galactic, Hot Tuna, Lotus, Stephen Marley, Grateful Dead Alumni Bob Weir and Ratdog, Widespread Panic, Stephen Stills, the Black Keys, Junior Brown, Griffin Anthony, The Doobie Brothers, Buddy Guy, Furthur, JJ Grey & Mofro, Little Feat and Zappa Plays Zappa.

[29][30][14] The 2014 event, held April 10–12, featured guests Allman BrothersLynyrd Skynyrd, Trey Anastasio Band, Tedeschi Trucks Band, Gov't Mule, Jaimoe's Jasssz Band, Umphrey's McGee, Ziggy Marley, Blues Traveler, Chris Robinson Brotherhood, Hot Tuna Electric, Moe., Rusted Root, Ivan Neville's Dumpstaphunk (Music of Led Zeppelin), Soulive, Royal Southern Brotherhood, Walter Trout, Rob Garza (of Thievery Corporation), Blind Boys of Alabama, Bobby Lee Rodgers Trio, Melvin Seals & JGB, Futurebirds, Matt Schofield, Break Science, Sean Chambers and The Yeti Trio.

Wanee Wednesday featured a tribute to Butch Trucks with The Freight Train Band feat Luther & Cody Dickinson, New Orleans Suspects, Crazy Fingers, Ben Sparaco, Matt Reynolds and Brothers and Sisters.

[39][40][35][41][42] The 2018 festival, which is set for April 19–21 at the Spirit of the Suwannee Music Park, featured two nights of Widespread Panic and Phil Lesh & The Terrapin Family Band.

Other bands announced include As the Crow Flies, Dark Star Orchestra (Thursday on the Peach Stage), St. Paul & The Broken Bones, Jaimoe's Jasssz Band, The Chris Robinson Brotherhood, North Mississippi All Stars, Karl Denson's Tiny Universe (Eat A Bunch of Peaches featuring George Porter Jr. & Marc Quinones), Pigeons Playing Ping Pong, Walter Trout, Sonny Landreth, The Marcus King Band, George Porter Jr. & Runnin’ Pardners), Pink Talking Fish (Tied To The Whipping Post), Soul Rebels, Les Bros, Bobby Lee Rodgers Trio, The Main Squeeze, Big Something, New Orleans Suspects, Berry Oakley's Indigenous Suspects, Midnight North, The Yeti Trio and Crazy Fingers.