[5] Particularly her study involved the knockdown of WDR5 in order to see if it inhibited virus-triggered activation of IRF3 and NF-kappaB, as well as transcription of the IFNB1 gene, thereby lowering the immune response which could result in over-inflammation of the lungs and thus acute respiratory distress.
Her findings in this study was that WDR5 is essential in assembling a virus-induced VISA-associated complex and in virus-triggered induction of type I IFNs.
One important research paper published by her was with reference to Insulin-Like Growth Factor-1 (IGF) Signaling in cases of lung inflammation, such as with acute respiratory distress.
[14] For those with kidney disease or a diet high in phosphate (such as in countries with food containing a significant amount of additives to their food (especially dairy), like the United States and some European countries, excessive IGF levels occur in order to prevent phosphotoxicity.
[2] In August 2020, Wang appeared on NBC News and denied claims by the U.S. Trump Administration that the Wuhan Institute of Virology was the origin of the COVID-19 virus, or that they had safety problems.