The station is located at Warburg on the double track and electrified Hamm–Warburg line to Hamm, the Frederick William Northern Railway to Kassel and the non-electrified Upper Ruhr Valley Railway to Hagen.

Regional trains stopping in Warburg are: Regional-Express trains to Düsseldorf (RE 11: Rhein-Hellweg-Express) and to Hagen (RE 17: Sauerland-Express) and Regionalbahn trains via Paderborn to Münster (RB 89: Ems-Börde-Bahn).

[5] InterCity trains also stop in Warburg.

Warburg station is part of the Paderborn-Höxter Regional Transport Association (Nahverkehrsverbund Paderborn-Höxter).

A bus station is located in front of the building, catering for bus services in the city of Warburg and the surrounding villages.