The current station originally opened in 1890 by the Missouri Pacific Railroad, and is built out of sandstone in the Richardsonian Romanesque style.

It has seen several remodels and enlargements the most recent major change being in 1984 when the baggage section and loading platform were added.

The station houses the Warrensburg Chamber of Commerce visitors center.

Service to Los Angeles can be obtained through a connection at Kansas City through the Southwest Chief.

Connections to Chicago are available in Kansas City via Southwest Chief and St. Louis via Lincoln Service trains.