[2] The highway travels east from the interchange onto Ice Harbor Drive after passing Hood Park on the shore of the Snake River and a local branch library.

The two-lane road is rural with a speed limit of 60 miles per hour (97 km/h) as it passes north of the McNary National Wildlife Refuge.

[3][4] The highway then turns northeast and ascends a ridge that overlooks the Snake River, which continues north while SR 124 travels east through the Eureka Flat.

The highway from Piper Canyon Road to Waitsburg follows a small section of the route that Lewis and Clark took from Fort Clatsop in May 1806 before splitting in Montana.

The original route started at US 410 in Touchet and went north to Eureka and east to SSH 3E west of Prescott.

The intersection, along with a nearby junction with Humorist Road that was replaced with an overpass, had been the sites of several fatal collisions that killed five people in the late 2000s.

[23] A railroad crossing south of the Ice Harbor Dam was replaced in October 2017 with an overpass that cost $11 million to construct and realigned a dangerous intersection with a nearby road.