The highway begins in the unincorporated community of Manson and travels southeast along the north shore of Lake Chelan into Chelan, where it is briefly concurrent with U.S. Route 97 Alternate (US 97 Alternate).

[1] US 97 Alternate splits off, traveling northeast, and SR 150 continues southeast towards Chelan Falls and crosses over the Cascade and Columbia River Railroad.

[3] The highway ends at an intersection with US 97 north of the Beebe Bridge on the Columbia River.

In 2011, WSDOT calculated that between 2,300 and 10,000 vehicles per day used the highway, mostly in Downtown Chelan on Woodin Avenue.

[14] WSDOT replaced an intersection with No See-Um Road northwest of Chelan with a roundabout in 2017.