Located at the intersection of Waterloo Road and Washington Boulevard, the neighborhood is encompassed mostly by Jessup and partially by Elkridge.

[2] During the American Revolution, Spurrier's tavern was significant as a supply and resting point for the Continental Army; George Washington was a frequent visitor.

In 2016, funding has been requested to construct a new high school on the Mission Road Quarry Site, currently owned by Savage Stone.

Waterloo is 1.9 miles (3.1 km) (a four-minute drive) from Jessup station (MARC Camden Line).

The area is also served by a number of bus routes that interchange at the Maryland Wholesale Food Market Transportation Hub.