The series stars Mark McKenna, Ciara Bravo, and Joshua J. Williams and it follows Wayne, "a 16 year-old Dirty Harry with a heart of gold", as he sets out to retrieve his late father's stolen car with the help of Del, a girl he has a crush on.

[9] Alongside the announcement of the series order, it was reported that Joshua J. Williams had been cast in a recurring role and that Dean Winters and Mike O'Malley would make guest appearances in the pilot episode.

Following the screening, a conversation was held featuring members of the cast and crew, including creator Shawn Simmons, actors Mark McKenna and Ciara Bravo, director Iain B. MacDonald, and writers and executive producers Greg Coolidge, Kirk Ward, Rhett Reese, and Paul Wernick.

"[17] In another encouraging criticism, Screen Rant's Kevin Yeoman commended the series saying, "With its varying tones, stellar lead performances, and great supporting cast, Wayne is much more than the foul-mouthed action-comedy it makes itself out to be.

The laughs may be pitch black at times, and the violence is occasionally shocking, but there’s a fascinating and entertaining sweetness woven into every scene that’ll hit you like a blast of rock salt to the heart.

"[18] In an additional acclamatory critique, Rolling Stone's Alan Sepinwall gave the series a rating of 3½ out of 5 stars and was similarly approving saying, "Both the show and Wayne’s attempts to right the world’s wrongs don’t always work, but they mean well and are rarely dull.