The Wazirs or Waziris (Pashto: وزير) are a Karlani Pashtun tribe found mainly in the Pakistan-Afghanistan border region.

The common ancestor of the Ahmadzai and Utmanzai is believed by them to be the eponymous W also ancestor to the Mahsud wazir tribe that has since taken a distinct and divergent path.

Through Wazir, the tribes trace their origins to Karlani and thence to the founder of the Pashtun lineage, Qais Abdur Rashid.

[5] Some western ethnologists consider them of being mix of Arachosian or Tatar ethnicity.

[1] Although the Utmanzai and Mehsud tribes have a traditional rivalry and live in geographically distinct regions,[6] the Ahmadzai and Mehsud communities co-exist peacefully and many head men are connected by marriage.