Frontman Deryck Whibley said the song is about war, death, fear, corporate power and other concerns, and was written after the band's trip to the Congo, making it the last song written for Chuck.

At the end of the video, the announcer says that the next guest is Pain For Pleasure, Sum 41's heavy metal alter ego band.

Fox83 of Sputnikmusic called the song an "impressive approach lyrically" and said "If System of a Down's 'Chop Suey!'

"[4] An Entertainment Weekly reviewer wrote, "It may sound heinous on paper, but trust us, the first single, 'We're All To Blame', is far better than it has a right to be.

"[5] IGN published a recommendation saying, "'We're All To Blame' is, bar none, the single best song Sum 41 has ever written and performed.