The wedding of Felipe, Prince of Asturias and Letizia Ortiz was held on 22 May 2004 in the Almudena Cathedral at the Royal Palace of Madrid, Spain.

The wedding was presided over by the archbishop of Madrid, Antonio María Rouco Varela, and was watched by 25 million people in Spain alone.

Felipe and Letizia occupied the presidential table, along with Queen Margrethe of Denmark and her husband, Prince Henrik; the King and Queen of Norway, Harald and Sonja; the President of Ireland and her husband, Mary and Martin McAleese, and the president of El Salvador, Francisco Flores Pérez, and his wife, Lourdes Rodríguez.

At the table of the Infanta Elena and her husband Jaime de Marichalar were Erika Ortiz, sister of the bride, and her husband, Antonio Vigo Pérez; the Prince of Liechtenstein, Hans-Adam II; the Prince and Grand Master of the Sovereign Military Order of Malta, Andrew Bertie, and the President of Ecuador, Lucio Gutiérrez, and his wife, Ximena Bohórquez Romero.

At the table of the Infanta Cristina and her husband Iñaki Urdangarin were Telma Ortiz, sister of the bride; the president of Colombia, Álvaro Uribe; the President of Nicaragua, Enrique Bolaños, and his wife, Lila T. Abaunza, and the Prime Minister of Spain, José Luis Rodríguez Zapatero, and his wife, Sonsoles Espinosa.

Headed by an officer followed by six halberdiers, it consisted of: The bride arrived at 11:12 in the morning to the cathedral in a Rolls-Royce Phantom IV, instead of on foot as planned, due to the persistent, intense rain.

After the religious ceremony, the newlyweds took a tour by car, a black Rolls-Royce Phantom IV, through the streets of Madrid escorted by the Motorcycle Section of the Royal Guard.

They continued through the Paseo del Prado to the Emperor Charles V square and took the Barcelona City Avenue to reach the Basilica of Our Lady of Atocha, where they were received by the Mayor of Madrid, Alberto Ruiz-Gallardón, the Cardinal Archbishop of Madrid, Monsignor Antonio Maria Rouco Varela, and the Priest of the Basilica, Father José Antonio Álvarez.

Once finished, the Prince and Princess of Asturias greeted the large audience present, then returned to the Royal Palace by the same route they had used on the outward journey.

The couple and their families greeted the large crowd gathered in the Plaza de Oriente from the balcony of the Royal Palace.

The King's toast expressed to Letizia the enormous happiness and enthusiasm of the entire Royal Family for this event, asked the new spouses to always think of Spain, and to dedicate "with love and devotion, the best of your efforts to the Spaniards, to join their hopes, share their illusions and be able to always fuse with their feelings and difficulties", with the certainty that "you are inspired by the passion to serve this great, diverse and plural country, proud of its coexistence in democracy and freedom."

The Prince finished with an emotional tribute to "the absent, those who were not criminally and brutally allowed to continue living their illusions and anxieties, and also those who today can not enjoy with them, free and civically of the Madrid spring that welcomes us and it raises our spirits" (in a clear reference to the victims of 11-M).

[14] The nuptial veil was a gift from the Prince to Letizia; with a triangular shape, three meters long by two wide, of natural silk tulle in ivory white with scrolls and hand-embroidered wreaths, which mixed the fleur-de-lis and the spike.

At 8:00 on the day of the wedding, a Lieutenant Colonel of the Army, escorted by two soldiers of the Royal Guard, deposited a wreath of flowers with the phrase: "Always in our memory, Felipe and Letizia" in the Forest of the Absent (currently Forest of Remembrance), a composition in the center of the Emperor Charles V square with trees and flowers, in memory of the victims of the terrorist attacks of 11-M.[18] Televisión Española produced the live institutional television signal that was distributed to all major networks in Spain, reaching a national record as the most-watched television program ever with 25.1 million viewers.