Formerly produced in partnership with Creation Entertainment, the Weekend of Horrors show is now owned exclusively by Fangoria Magazine and is held once annually in Los Angeles, California.

The convention also deals in areas of the horror genre outside filmmaking, as well as exploitation, science fiction, and fantasy entertainment.

Fangoria magazine editor Tony Timpone was the Master of Ceremonies and Co-Producer of the shows during its time with Creation Entertainment.

Starting with the 2006 Weekend of Horrors in Secaucus, New Jersey, the convention expanded from a two-day (Saturday and Sunday) event, to a three-day (including Friday).

Until 2008, Weekend of Horrors occurred annually in Rosemont, Illinois (Winter), Los Angeles, California (Spring), and New York City, New York (formerly Secaucus, New Jersey) (Summer), with an additional destination chosen based on the year (in 2008, Austin, Texas, was added to the circuit).