[3] Samuel W. Foster bought a mill site on the Huron River at what is now Scio in 1835.

[9] Thirdly, by coincidence scio also means "I know" in Latin, so following the American Civil War some people assumed this was the origin of the name.

This date followed the establishment by the United States of America of diplomatic relations with the modern nation of Greece, following the Greek War of Independence (1821–1830).

Webster referred to the 1822 destruction of Scio, the then-current French translation of Chios (Greek: Χίος, pronounced /ˈçio̞s/), derived from the Genoese dialect.

Eugène Delacroix's 1824 painting The Massacre at Chios and numerous publications brought the Greek cause to the attention of Americans.

[citation needed] The City of Ypsilanti was named after the victor of the final battle of the revolution, Alexander's brother Demetrius.

[10] The sister townships of Scio and Webster were named as a monument to the birth of the new Greek republic, the end of its citizen's subjection, and the first American senator to support their nation.

In 1842, Norman C. Goodale, known as the founder of Delhi Mills, acquired all the unsold lots.

[11] A portion of Scio Township's area and population decreased slightly after the census when the village of Dexter incorporated as an autonomous city in 2014.