Wernersville is a borough in Berks County, Pennsylvania, United States.

City dwellers (especially from Philadelphia and New York City) traveled out to Wernersville, a stop on the Reading Railroad to rest and partake of the cool mountain air of South Mountain.

Some were advertised as sanatoriums, specializing in rest cures for illnesses such as tuberculosis.

Most of these resort hotels have since disappeared due to fire, demolition, or have been transformed into buildings for institutional purposes.

The Lerch Tavern and Wertz Mill are listed on the National Register of Historic Places.

28.2% of all households were made up of individuals, and 10.2% had someone living alone who was 65 years of age or older.