His professional career began in the early 1980s in the Tampa Bay area where he founded 1991 Southwestern Music Conference's showcase act Autodrive along with drummer/producer Mark Prator.

The following year, Wesley embarked on a solo career and became the opening act for British rockers Marillion on seven consecutive tour legs around the world, especially North and South America, the UK and Europe.

On Wesley's sixth full-length studio album Disconnect, released in 2014, Alex Lifeson made a guest appearance, playing a guitar solo on the track Once a Warrior.

In 2018, Wesley performed lead vocals with international artists ÚMÆ on their debut album titled Lost in the View, which was released on January 3, 2019.

In July 2019, Wesley and drummer Mark Prator played with Edison's Children, the sci-fi band of Neil Armstrong's son (Rick Armstrong) which is known for writing music about the supernatural & extra-terrestrial co-headlining with the Alan Parsons Project in an outdoor concert festival near the Kennedy Space Center celebrating the 50th anniversary of Rick's Father and Apollo 11's landing a crewed spacecraft on the Moon for the first time.