The Weser-Leine-Express (RE 70) is the name used in North Rhine-Westphalia (NRW) for a Regional-Express service that connects the east Westphalian regional centre of Bielefeld and Minden and the Lower Saxony regional centres of Hanover and Braunschweig.

The service alternates with the Ems-Leine-Express, which connects Rheine with Minden and Braunschweig.

The border between North Rhine-Westphalia and Lower Saxony Between is crossed between Minden and Bückeburg.

Since the introduction of the integrated regular-interval timetable in the whole of North Rhine-Westphalia (NRW-Takt) in 1998, the connection between Bielefeld and Braunschweig has been operated as the RE 70 under the name of the Weser-Leine Express,[3] after the Weser and Leine rivers.

The statewide fares of Lower Saxony (e.g. the Niedersachsen-Ticket) also apply between Löhne and Braunschweig.