[1] Mentioned in the Domesday Book, West Derby achieved significance far earlier than Liverpool itself.

There still remains a courthouse built in the reign of Queen Elizabeth I: the first (Wapentake) court in West Derby was established around 1,000 years ago.

Opposite the courthouse is a set of Victorian cast iron stocks once used as a public restraint for offenders.

[9] West Derby once had a Motte and Bailey castle, now completely disappeared, at Castlesite Road and Meadow Lane[10][11] In 1327 it was reported to be in ruins.

The site is now a small public park, the shape and dimensions of which are similar to that of a Roman barracks or castra.

[13] The part of West Derby that is in the Croxteth Country Park ward is within the Liverpool Walton Parliamentary constituency currently represented by Dan Carden.

Alder Hey Children's Hospital is located on the south side of West Derby, at Eaton Road.

The station building has since become a shop and the access ramps to the former platforms remain, although one of the passages have been closed off to the public.

The former Channel 4 soap opera Brookside was filmed on a housing development built on part of Lord Sefton's estate.