It is bounded by Jamboree Road to the northwest, California State Route 261 to the southeast, and Irvine Boulevard to the southwest.

Despite its name, West Irvine is located in the northern reach of the city, bordering Tustin.

West Irvine is adjacent to The Market Place, a major shopping center in the region.

[1][2] The Orange County Fire Authority is headquartered in West Irvine, sandwiched between Jamboree Road and SR-261 in a peninsula of the neighborhood's jurisdiction.

Along with the neighborhood's proximity to the SR-261 toll road, Interstate 5 is on the opposite side of the adjacent Market Place shopping center.