In the Town of Hedgesville, WV 901 is named North Mary Street.

Between Hedgesville and Falling Waters, WV 901 is named Hammonds Mill Road.

WV 901 turns southeast passing through Spring Mills.

Then WV 901 enters Falling Waters having an interchange with Interstate 81.

[2] In 2014, the road was ceremonially renamed the Deputy John L. Burkett III Memorial Highway in honor of a Berkeley County sheriff's deputy who was killed in the line of duty in 2001.