Weston Henry Noble was born and raised on a farm located just west of Riceville, Iowa to parents of English ancestry.
Later, he was confirmed in the Free Methodist Church and received his early education in a country one-room schoolhouse until the eighth grade, afterward attending the local Riceville High School.
Graduating from high school at the age of 16, his original intention was to enroll at The University of Iowa, then the largest and most prominent institution of higher learning in the state.
Due largely to the intense patriotism of World War II and anticipating eventual conscription, Noble volunteered for military service and was called to active duty in February 1943, in the spring semester of his senior year.
After arriving home and teaching high school for a year in Iowa, Noble's father sent him a letter notifying him that he had a large package to pick up.
During a highly distinguished 57-year career, Noble served as music director of the Luther College Concert Band from 1948–1973 and the Nordic Choir from 1948-2005.
Following his retirement, Noble served a one-year appointment as visiting conductor-in-residence at Carthage College in Kenosha, Wisconsin during the 2007-08 academic year.
His distinguished career included conducting more than 900 music festivals throughout the United States, Australia, Canada, Europe, Russia, Asia, and South America.
In December 2010, at the age of 88 years, Noble traveled to South Korea for the first time, conducting a concert of Handel's "Messiah" for the Camarata Music Company.