The school's teams play within the NCAA Division III and in the New England Women's and Men's Athletic Conference (NEWMAC).

Eight years later, women's basketball made its first Final Four, followed by the 1997 softball team finishing third at the national tournament in Eau Claire, Wisconsin.

[3] On October 14, 2016, the Wheaton College Athletic Department announced the first-ever mascot name for the Lyon... Roary.

Highlighting that list is Amber James '04, who was pivotal during Wheaton's run of winning six consecutive NCAA indoor and outdoor national championships from 2001–03.

James, a 17-time national champion and 24-time all-American, was recognized by the NCAA as the greatest female athlete in the 25-year history of the Division III indoor track & field championship in 2009.

Chris Denorfia '02 was a 19th round pick in the 2002 Major League Baseball amateur draft by the Cincinnati Reds.

Deborah Simourian finished in a 72-hole tie for the AIAW individual collegiate golf championship in 1975 before losing a 3-hole playoff.

In addition, Dan Antoniuk put together a long career in professional soccer, playing with teams like the Portland Timbers and Montreal Impact.